Name: Climbazole
CAS No.: 38083-17-9
Alias: 1-(4-clorophenoxy)-3,3-dimethyl-1-(imidazole-1-yl)-2-butanone
Grade: Daily care | Content ≥99.9%min. by GC
Storage: normal temperature (8-25℃)
EINECS number: 253-775-4
Molecular Formula: C15H17ClN2O2
Molecular weight: 292.761 g/mol
Specification: USP BP EP
General Overview of Climbazole CAS 38083-17-9
Climbazole has broad-spectrum bactericidal properties. It is mainly used in anti-itching and anti-dandruff conditioning shampoos and hair care shampoos, and can also be used in high-end detergents such as antibacterial soaps, shower gels, medical toothpastes, and mouthwashes. It has strong inhibitory power and good effect on fungi (Pytyrosponcim, ovale) that produce dandruff. It is soluble in surfactants, the method of application is simple, and there is no worries about delamination. Stable to metal ions, no yellowing or discoloration. The recommended dosage is 5‰-10‰, and the dissolution temperature is ≤70°C.
Climbazole CAS 38083-17-9 is a white crystalline powder. Its chemical structure and properties are similar to other fungicides such as ketoconazole and miconazole. Climbazole is most commonly found as an active ingredient in OTC anti-dandruff and anti-fungal products, including shampoos, lotions and conditioners. It may be accompanied by other active ingredients such as zinc pyrithione or triclosan.
Specification of Climbazole CAS 38083-17-9
Content assay 99.50%min
Loss on drying 0.5% max
Parachorophenol,% ≤0.1
Soluble,% ≤1.5
Monomers, % ≤0.1
PH(1%aqueous solution) 5-8
Arsenic ,ppm ≤3
Heavy metal(pb) ppm ≤10
Nitrogen, % 11.0-12.8
Sulfate ash, % ≤0.4
Climbazole CAS 38083-17-9 Application
- Climbazole is a potent inducer and inhibitor of P450-dependent drug metabolizing enzymes, which is also used as antifungal and antidandruff agent.
- Climbazole is mainly used for relieving itching recuperated anti-dandruff shampoo, hair shampoo, can also be used for antibacterial soap, shower gel, liquid medicine toothpaste, mouthwash, etc. Recommended dose: 0.4-0.8%.