Procaine alkaloids and procaine can be considered as different expressions of the same substance in chemical essence, but their emphasis may differ in everyday contexts and medical applications. The following is a detailed analysis of the relationship between the two:
Firstly, the essence is the same
Procaine base, also known as procaine, has the same chemical structure and its main component is procaine hydrochloride. In chemistry, they refer to the same substance. Procaine base is the base form of procaine, while procaine usually refers to its hydrochloride form, namely procaine hydrochloride.
Secondly, differences in expression
1. Name difference:
-Procaine base: More emphasis is placed on its base form, which may be specifically mentioned in certain chemical or pharmaceutical discussions.
-Procaine: In daily medical applications, this name is more commonly used, usually referring to its hydrochloride form, namely procaine hydrochloride.
2. Application context:
-In chemical or pharmaceutical research, procaine base may be mentioned as needed to emphasize its specific chemical properties or reactions.
-In clinical practice, medical professionals such as doctors and pharmacists usually use the name "procaine" directly, referring to the hydrochloride procaine used for anesthesia.
Thirdly, medical applications
Procaine hydrochloride, as a short acting ester local anesthetic, has been widely used in clinical practice. Its main mechanism of action is to block nerve excitation and conduction by inhibiting sodium ion channels in the nerve cell membrane. It can be used for various anesthesia methods such as epidural anesthesia, subarachnoid block, infiltration anesthesia, nerve block anesthesia, etc. In addition, procaine can also be used for local block therapy to treat certain injuries and inflammations.
Fourth, precautions
-Procaine usually requires a skin allergy test before use to avoid allergic reactions.
-The metabolite of procaine, PABA, can weaken the antibacterial efficacy of sulfonamide drugs, so it should be avoided to use it together with sulfonamide drugs.
-The anesthetic effect of procaine is relatively short, and can be prolonged by adding a small amount of adrenaline.
In summary, procaine base and procaine are different expressions of the same substance in chemical essence, but may be emphasized in practical applications due to context and needs. In medical applications, it usually refers to its hydrochloride form - procaine hydrochloride.