Procaine base, commonly referred to as procaine, is used as a local anesthetic and has a variety of specific clinical uses. The following is a detailed description of the special uses of procaine:
First, the anesthetic effect
1. Local anesthesia:
Procaine is a short-acting ester local anesthetic that temporarily blocks nerve fiber conduction and has an anesthetic effect. It is mainly used in local infiltration anesthesia, block anesthesia, subarachnoid anesthesia, epidural anesthesia and block therapy. It has been widely used in clinic because of its rapid action, short action time and small effect on the heart.
- In dental, ophthalmology, ENT and other procedures, procaine is often used as a local anesthetic to reduce the pain of patients.
2. Combined anesthesia:
- Procaine can also be used in combination with intravenous general anesthetics, inhaled general anesthetics, and analgesics to administer anesthesia to enhance the anesthetic effect.
Second, the therapeutic effect
1. Disease Treatment:
Procaine is not only used for anesthesia, but also has a wide range of clinical applications in the treatment of many diseases. For example, in gastroenterology it can be used to treat pancreatitis; In the respiratory department can be used to treat hemoptysis; In surgery, neurology also has its application space, such as the treatment of renal colic.
- Procaine can also be used in "block therapy", by injecting into the diseased area or around the nerve trunk, to block the transmission of nerve impulses, reduce local inflammation and damage, and enhance the therapeutic effect.
2. Analgesic effect:
- Procaine has a sealing effect on the nerve endings of the injured mucosal surface, and can block the stimulation of the lesion to the central nervous system, thereby rapidly relieving pain. For example, in gentamicin procaine capsules, procaine does just that.
Third, special formula drugs
Procaine Penicillin: This is an antibacterial drug consisting of penicillin and procaine. Procaine is used here as a carrier to slow the release and absorption of penicillin, thereby extending the action time of penicillin and reducing the number of doses. Procaine penicillin is used clinically for mild to moderate infections caused by pathogens that are highly sensitive to penicillin.
Fourth, precautions
- Allergic reaction: Procaine has a certain allergic rate, so it is necessary to do an allergy test before use, and those with positive results cannot use.
- Side effects: Nausea, sweating, dyspnea, flushing, delirium, excitement, convulsions and other adverse reactions may occur during the treatment, and even anaphylactic shock may occur. Therefore, it must be used reasonably under the guidance of a doctor and the dosage must be strictly controlled.
Drug interaction: When using procaine, attention should be paid to the interaction with other drugs to avoid the occurrence of adverse reactions.
In summary, procaine, as a local anesthetic, has a variety of special clinical uses, including anesthesia, therapeutic effects and applications in special formulations of drugs. However, due to its allergy rate and side effects, it must be strictly followed when using to ensure the safety of patients.