Name: Local Anesthetic Drug 99.6% Purity CAS 1786-81-8 Prilocaine/Propitocaine HCl/Propitocaine Hydrochloride
Brand: Xi'an Frankherb Local Anesthesia Biotech Co., Ltd.
SKU: FH-M2110
Price: 90.50 USD
Availability: InStock
Rating: 5 (1 reviews)

Description

Product Introduction:
Prilocaine hydrochloride CAS 1786-81-8 is a local anesthetic of the amino amide type.
Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia, for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA). In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue. Maximum dosage for dental use: 8.0 mg/kg (2.7 mg/lb), with a maximum dose of 500 mg. Eutectic Mixture of Local Anesthetics (EMLA) containing 5% lidocaine and prilocaine in a cream was found to give effective topical analgesia in normal and diseased skin, making it useful for superficial surgery and various other clinical procedures. To be effective, an adequate amount must be applied under occlusion and at the right time before the intervention.

Product Applications:
This medication contains 2 amide-type local anesthetics, lidocaine and prilocaine. It is used on normal, unbroken skin or on the outer genital area to prevent pain before certain procedures such as inserting a needle, skin grafts, or skin laser surgery. It works by temporarily numbing the skin and surrounding area. Do not use this product in the ears.
If this product alone cannot completely numb the area being treated, it may be used to numb the area before a lidocaine injection is given to provide enough pain relief for certain procedures (e.g., removal of genital warts).

Usage and Dosage:
Infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use 10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.

Product name	Prilocaine/Propitocaine Hydrochloride	Standard	USP36
Package	1kg/bag	Quantity	100kg
Cas No.	1786-81-8	EINECS	217-244-0
Molecular Formula	Cl3H20N2O·HCl	Molecular Weight	256.7716
Function	Main functions are as follows: 1. Local anesthetic.
Applications	Main applications are as follows: The material for Local anesthetic.
Items Tested	Specification		Result
Characters	White or almost white crystalline powder		Confirms
Melting Point	166℃-169℃		166.5℃-168.5℃
Solubility	Freely soluble in water and in alcohol		Confirms
Assay (HPLC)	99.0--101.0% (calculated on the dried basis)		99.6%
Loss on Drying	Not more than 0.3%		0.16%
Related substances	Not more than 1.0%		0.11%
Acetone	Not more than 5000ppm		conforms
Ethanol	Not more than 5000ppm		conforms
Sulphated ash	Not more than 0.15%		conforms
Heavy Metal	Not more than 0.001%		＜0.001％
Conclusion	Conforms USP36

Local Anesthetic Drug 99.6% Purity CAS 1786-81-8 Prilocaine/Propitocaine HCl/Propitocaine Hydrochloride

Description

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