Local anesthetic action time of procaine base
By enze
September 25th, 2024
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Procaine base, also known as procaine, is a commonly used local anesthetic with a relatively short duration of local anesthetic action. The local anesthesia time of procaine can be analyzed from several aspects:
Onset time and maintenance time
Onset time: The onset time of procaine after injection is usually 1-3 minutes, which means that the time from injection to the beginning of the anesthetic effect is relatively short.
Maintenance time: The anesthetic maintenance time of procaine is between half an hour and an hour, depending on a number of factors, such as injection dose, injection site, individual differences, etc. Generally speaking, the anesthetic duration of procaine is about 30-45 minutes.
Influencing factor
Drug concentration and dose: The concentration and dose of procaine directly affect the duration of local anesthesia. The higher the concentration and the larger the dose, the longer the duration of local anesthesia may be, but at the same time, the patient's tolerance and possible adverse reactions need to be considered.
Individual differences: Different patients have different sensitivity to procaine and metabolic rate, so the duration of local anesthesia will be different.
Injection method: The injection method of procaine (such as local infiltration anesthesia, nerve block anesthesia, etc.) will also affect its local anesthesia action time.
Practical application
Procaine is commonly used in a variety of surgeries and treatments that require local anesthesia. Because of its relatively short duration, it may need to be combined with other long-acting local anesthetics or repeated injections in some surgeries that require longer periods of time to maintain the anesthetic effect.
Matters needing attention
When using procaine for local anesthesia, the doctor's instructions and drug instructions should be strictly followed to ensure the safety and effectiveness of the drug.
Observe patients' reactions and changes in vital signs, and deal with possible adverse reactions in time.
Procaine should be contraindication in patients who are allergic to the drug.
In summary, the local anesthetic action of procaine is relatively short, usually between half an hour and an hour, depending on a number of factors. When used, reasonable selection and adjustment should be made according to the actual situation and surgical needs of patients.
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